Aim: Epidemiological studies are important for the prevention and resolution of health problems. We carried out this study to evaluate the incisional and excisional biopsies applied to the nasal skin in the Kırşehir region. Material and Method: Between December 2014 and October 2017, 354 patients and 354 lesions were evaluated with a mass on the nasal skin retrospectively. The mean age of the patients, gender distribution, localization of lesions and histopathological type were investigated. These masses were classified as non-neoplastic, benign, premalignant, and malignant. Results: The number of females were 226, and the number of males were 128. Age distribution ranged from 9 to 90. There were 20 cases under 18 years old. Premalignant and malignant lesions were not observed in adolescent/pediatric age group. Eighty-two cases over 60 years of age were identified, and 60% of them had a malignant tumor. Nasal skin lesions were more common in the 31-40 age range (24.9%). The most common lesion group was benign tumors (65.2, n=231), followed by malignant tumors (20.1%, n=71), non-neoplastic lesions (9.6%, n=34) and premalignant lesions (5.1%, n=18). Nevus (175), basal cell carcinoma (67) and chronic nonspecific inflammations (21) were the most common diagnoses. Among the malignant tumors, basal cell carcinoma was diagnosed (67) (M/F:1.09, mean age:65.8) more than squamous cell carcinoma (4). In the patient group with benign tumors, there were vascular tumors (13: capillary hemangioma; 10, hemangioma; 3), verruca vulgaris (12), skin appendage tumors (11: trichoepithelioma; 4, trichofolliculoma; 2, steatocystoma; 1 hydradenoma papilliferum; 1, chondroid syringoma; 3), seborrheic keratosis (8), fibroepithelial polyp (7), fibroma (4) and dermatofibroma (1) respectively after nevus. In 18 premalignant lesions, 11 cases were diagnosed as actinic keratosis, and 7 cases were diagnosed as keratoacanthoma. Discussion: The literature on demographic and histopathological evaluation of nasal lesions is limited. The increase in epidemiological studies can offer a comparative advantage over other studies and can be a guide for health management. Patients with a mass on the nose are required to undergo differential diagnosis with a biopsy.